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[DOI] [PMC free article] [PubMed] [Google Scholar] 50.Talbot K, Wang HY, Kazi H, Han LY, Bakshi KP, Stucky A, Fuino RL, Kawaguchi KR, Samoyedny AJ, Wilson RS, Arvanitakis Z, Schneider JA, Wolf BA, Bennett DA, Trojanowski JQ, and Arnold SE

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In addition to systemic adverse effects, inhibiting BCL-2 family members could be problematic for diseases and conditions of the CNS

Mechanisms and evidence bases are not interchangeable

Less necrosis developed in treated wounds, suggesting the peptide helped preserve marginally viable tissue that might otherwise have died